From version 2.6.16 Linux kernel has a tunable parameter named
/proc/sys/vm/drop_caches
If you want to force to clear pagecaches from memory use:
echo 1 > /proc/sys/vm/drop_caches
If you want to clear dentry and inode caches from memory:
echo 2 > /proc/sys/vm/drop_caches
and if you want to clear both of the pagecaches and dentry and inode caches just use:
echo 3 > /proc/sys/vm/drop_caches
In order to make sure all cached objects are freed you must execute the sync
command first.